SCHEMBL28021234

SCHEMBL28021234

C=CC(=O)OCCCOCCCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.56
LMNA P02545 1/20 0.55
AKR1B10 O60218 4/20 0.53
AKR1B1 P15121 4/20 0.53
ALDH1A1 P00352 4/20 0.53
TSHR P16473 4/20 0.53
TP53 P04637 2/20 0.53
HIF1A Q16665 2/20 0.53
HSD17B10 Q99714 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
RECQL P46063 1/20 0.50
RAB9A P51151 1/20 0.50
HCAR2 Q8TDS4 1/20 0.49
CYP3A4 P08684 1/20 0.49
ALOX5 P09917 1/20 0.47
HPGD P15428 1/20 0.45
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP12 P39900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17439437 0.95 ALDH1A1 (0.59) THRBLMNAAKR1B10AKR1B1ALDH1A1
SCHEMBL146669 0.94 THRB (0.63) THRBLMNAAKR1B10AKR1B1ALDH1A1
SCHEMBL27929355 0.91 THRB (0.59) THRBLMNAAKR1B10AKR1B1ALDH1A1
Acetic Acid SCHEMBL28013203 0.89 THRB (0.58) THRBLMNAAKR1B10AKR1B1ALDH1A1
Formic Acid SCHEMBL28238298 0.89 THRB (0.58) THRBLMNAAKR1B10AKR1B1ALDH1A1
SCHEMBL147883 0.89 THRB (0.61) THRBLMNAAKR1B10AKR1B1ALDH1A1
Sulfuric Acid SCHEMBL28055049 0.88 THRB (0.56) THRBLMNAAKR1B10AKR1B1ALDH1A1
SCHEMBL27759950 0.88 THRB (0.56) THRBLMNAAKR1B10AKR1B1ALDH1A1
SCHEMBL233466 0.88 ALDH1A1 (0.61) THRBLMNAAKR1B10AKR1B1ALDH1A1
SCHEMBL342569 0.88 ALDH1A1 (0.61) THRBLMNAAKR1B10AKR1B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103365133-B Production process for colorant, colorant composition, toner, ink for ink jet recording and color filter KONICA MINOLTA BUSINESS TECH 2015-06-17 CN disclosed