Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 15/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.45 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22122848 | 0.89 | CHRM1 (0.58) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL13162900 | 0.79 | CHRM1 (0.65) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL7213953 | 0.76 | HTR4 (0.61) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL28602013 | 0.74 | CHRM1 (0.60) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL13543095 | 0.74 | CHRM1 (0.62) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL2458991 | 0.74 | CNR1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL26185465 | 0.73 | GNAI3 (0.44) | TYRO3MERTK | |
| Hydrochloric Acid SCHEMBL26185526 | 0.73 | GNAI3 (0.44) | TYRO3MERTK | |
| SCHEMBL3330915 | 0.73 | SMN1; SMN2 (0.56) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL7987100 | 0.72 | LMNA (0.51) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662024-A | Tyrosine Kinase Inhibitors | HOFFMANN LA ROCHE | 2015-05-27 | — | — | CN | disclosed |