Methylpiperazine

Methylpiperazine

SCHEMBL28021385

C.CN1CCNCC1.Fc1ccc(F)c(F)c1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.42
SLC6A4 P31645 3/20 0.42
KCNH2 Q12809 2/20 0.42
SLC6A3 Q01959 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTR6 P50406 1/20 0.39
MC4R P32245 1/20 0.38
HTR1A P08908 2/20 0.37
HTR7 P34969 1/20 0.37
HTR2C P28335 2/20 0.37
HTR2B P41595 2/20 0.37
KDR P35968 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
MPO P05164 1/20 0.36
HTR3E A5X5Y0 1/20 0.36
HTR3B O95264 1/20 0.36
HTR3A P46098 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpiperazine SCHEMBL28820745 0.85 MEN1 (0.37) SLC6A2SLC6A4KCNH2SLC6A3MEN1
Methylpiperazine SCHEMBL28021840 0.85 SIGMAR1 (0.46) SLC6A2SLC6A4KCNH2SLC6A3HTR6
Methylpiperazine SCHEMBL28078163 0.82 SIGMAR1 (0.47) SLC6A2SLC6A4KCNH2SLC6A3HTR6
Methylpiperazine SCHEMBL28021851 0.81 HTR1A (0.44) SLC6A2SLC6A4KCNH2SLC6A3KMT2A
Methylpiperazine SCHEMBL28021404 0.81 HRH4 (0.38) SLC6A2SLC6A4KCNH2SLC6A3ALDH1A1
Methylpiperazine SCHEMBL28021414 0.81 ADRB1 (0.42) SLC6A2SLC6A4KCNH2MEN1KMT2A
Methylpiperazine SCHEMBL28021425 0.81 HTR2C (0.38) SLC6A2SLC6A4SLC6A3MEN1KMT2A
Methylpiperazine SCHEMBL28021849 0.81 SLC6A2 (0.41) SLC6A2SLC6A4KCNH2SLC6A3ALDH1A1
Methylpiperazine SCHEMBL28021853 0.79 HTR1A (0.45) SLC6A2SLC6A4KCNH2SLC6A3KMT2A
Piperidine SCHEMBL28021397 0.77 KDM4E (0.38) SLC6A2SLC6A4SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744613-A Half-metallocene catalyst containing fluorobenzene amidine, preparation method and application thereof SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD 2015-07-01 CN claimed