Methylpiperazine

Methylpiperazine

SCHEMBL28820745

C.CN1CCNCC1.Fc1cc(F)c(F)cc1F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
ADRB1 P08588 6/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KCNH2 Q12809 1/20 0.34
HTR2C P28335 1/20 0.33
OPRL1 P41146 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpiperazine SCHEMBL28021849 0.86 SLC6A2 (0.41) ALDH1A1LMNAADRB1SLC6A2SLC6A4
Methylpiperazine SCHEMBL28021385 0.85 SLC6A2 (0.42) MEN1KMT2AALDH1A1SLC6A2SLC6A4
Methylpiperazine SCHEMBL28021404 0.84 HRH4 (0.38) ALDH1A1LMNASLC6A2SLC6A4SLC6A3
Methylpiperazine SCHEMBL28021425 0.83 HTR2C (0.38) MEN1KMT2AALDH1A1LMNAADRB1
Methylpiperazine SCHEMBL28021414 0.83 ADRB1 (0.42) MEN1KMT2AADRB1SLC6A2SLC6A4
Methylpiperazine SCHEMBL28021840 0.82 SIGMAR1 (0.46) LMNASLC6A2SLC6A4SLC6A3KCNH2
Methylpiperazine SCHEMBL28021851 0.79 HTR1A (0.44) KMT2AALDH1A1ADRB1SLC6A2SLC6A4
Methylpiperazine SCHEMBL28078163 0.79 SIGMAR1 (0.47) LMNASLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL154155 0.77 PHGDH (0.41) ALDH1A1LMNAADRB1
Methylpiperazine SCHEMBL1363 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744613-A Half-metallocene catalyst containing fluorobenzene amidine, preparation method and application thereof SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD 2015-07-01 CN claimed