Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL28078163 | 0.98 | SIGMAR1 (0.47) | SIGMAR1HTR7HTR1ASLC6A2SLC6A4 | |
| Methylpiperazine SCHEMBL27594948 | 0.87 | SIGMAR1 (0.47) | SIGMAR1HTR7HTR1ASLC6A2SLC6A4 | |
| Methylpiperazine SCHEMBL28021849 | 0.86 | SLC6A2 (0.41) | SIGMAR1HTR7HTR1ASLC6A2SLC6A4 | |
| Methylpiperazine SCHEMBL28021385 | 0.85 | SLC6A2 (0.42) | SIGMAR1HTR7HTR1ASLC6A2SLC6A4 | |
| Methylpiperazine SCHEMBL28021851 | 0.84 | HTR1A (0.44) | HTR7HTR1ASLC6A2SLC6A4SLC6A3 | |
| Methylpiperazine SCHEMBL28021414 | 0.83 | ADRB1 (0.42) | SIGMAR1HTR7HTR1ASLC6A2SLC6A4 | |
| Methylpiperazine SCHEMBL28021425 | 0.83 | HTR2C (0.38) | SIGMAR1HTR1ASLC6A2SLC6A4SLC6A3 | |
| Methylpiperazine SCHEMBL28820745 | 0.82 | MEN1 (0.37) | SLC6A2SLC6A4SLC6A3KCNH2LMNA | |
| Methylpiperazine SCHEMBL28021853 | 0.81 | HTR1A (0.45) | HTR7HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL154155 | 0.77 | PHGDH (0.41) | SIGMAR1HTR3ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744613-A | Half-metallocene catalyst containing fluorobenzene amidine, preparation method and application thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2015-07-01 | — | — | CN | claimed |