Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974535 | 0.85 | LMNA (0.44) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL4768937 | 0.81 | RAB9A (0.47) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL9043817 | 0.81 | LMNA (0.45) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL9200724 | 0.79 | RAB9A (0.46) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL30356279 | 0.79 | LMNA (0.44) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL27488817 | 0.79 | SMN1; SMN2 (0.48) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8772851 | 0.79 | LMNA (0.53) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL15209660 | 0.78 | LMNA (0.43) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL24276055 | 0.76 | KDM4E (0.40) | LMNARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL24276140 | 0.76 | KDM4E (0.44) | LMNARAB9ANPC1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104788378-A | N-methyl-3-ethyl-4-hlorine pyrrole derivative compound | HUNAN HAILI CHEMICAL INDUSTRY CO LTD | 2015-07-22 | — | — | CN | disclosed |