Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069768 | 0.80 | LMNA (0.48) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL15220664 | 0.80 | LMNA (0.60) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL4768937 | 0.80 | RAB9A (0.47) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL9043817 | 0.80 | LMNA (0.45) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL28021919 | 0.79 | LMNA (0.48) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL8077558 | 0.79 | LMNA (0.44) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| Hydrochloric Acid SCHEMBL9200724 | 0.78 | RAB9A (0.46) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL27488817 | 0.78 | SMN1; SMN2 (0.48) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL30356279 | 0.78 | LMNA (0.44) | LMNARAB9ANPC1SMN1; SMN2ATM | |
| SCHEMBL15220624 | 0.78 | LMNA (0.54) | LMNARAB9ANPC1SMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492125-B1 | Insecticidal and synergistic miticidal compositions | AMERICAN CYANAMID CO (US) | 1997-08-27 | — | — | EP | disclosed |
| US-5591765-A | ARYLPYRROLECARBONITRILE | AMERICAN CYANAMID COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| US-5187184-A | Mixtures of substituted arylpyrroles and arylpyrazoles | AMERICAN CYANAMID COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0492125-A1 | Insecticidal and synergistic miticidal compositions | AMERICAN CYANAMID COMPANY (US) | 1992-07-01 | — | — | EP | disclosed |