SCHEMBL4768937

SCHEMBL4768937

CCc1nn(C)c(C(=O)O)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.47
NPC1 O15118 5/20 0.47
LMNA P02545 5/20 0.45
SMN1; SMN2 Q16637 6/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
ATM Q13315 2/20 0.41
POLB P06746 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 4/20 0.40
ALDH1A1 P00352 1/20 0.40
HTT P42858 1/20 0.39
NR1I2 O75469 1/20 0.39
AHR P35869 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2C9 P11712 1/20 0.37
GFER P55789 1/20 0.37
NR3C1 P04150 2/20 0.36
GAA P10253 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9200724 0.98 RAB9A (0.46) RAB9ANPC1LMNASMN1; SMN2L3MBTL1
SCHEMBL28842596 0.88 RAB9A (0.42) RAB9ANPC1LMNASMN1; SMN2L3MBTL1
SCHEMBL9043817 0.85 LMNA (0.45) RAB9ANPC1LMNASMN1; SMN2L3MBTL1
SCHEMBL27488817 0.84 SMN1; SMN2 (0.48) RAB9ANPC1LMNASMN1; SMN2L3MBTL1
SCHEMBL30356279 0.84 LMNA (0.44) RAB9ANPC1LMNASMN1; SMN2L3MBTL1
SCHEMBL27907866 0.83 RAB9A (0.52) RAB9ANPC1LMNASMN1; SMN2L3MBTL1
SCHEMBL15209660 0.82 LMNA (0.43) RAB9ANPC1LMNASMN1; SMN2L3MBTL1
SCHEMBL28021919 0.81 LMNA (0.48) RAB9ANPC1LMNASMN1; SMN2L3MBTL1
SCHEMBL974535 0.80 LMNA (0.44) RAB9ANPC1LMNASMN1; SMN2L3MBTL1
SCHEMBL24553584 0.78 L3MBTL1 (0.39) RAB9ANPC1LMNASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-221208002-U Pesticide intermediate 4-chloro-3-ethyl-1-methylpyrazole-5-formic acid production line 江苏广域化学有限公司 2024-06-25 CN claimed
CN-114561435-B Method for preparing 4-chloro-3-ethyl-1-methylpyrazole-5-formic acid by using magnetic carbon nanotube immobilized enzyme catalysis 南京科力硕生物科技有限公司 2022-08-30 CN claimed
CN-114561435-A Method for preparing 4-chloro-3-ethyl-1-methylpyrazole-5-formic acid by using magnetic carbon nanotube immobilized enzyme catalysis 南京科力硕生物科技有限公司 2022-05-31 CN claimed
CN-106614625-A Novel nanoscale tetrazine type acaricide for aviation 江苏蒲公英无人机有限公司 2017-05-10 CN claimed
CN-106187894-A The preparation method of 1 methyl 3 ethyl 4 chlorine 5 pyrazole carboxylic acid ethyl ester 潍坊鑫诺化工有限公司 2016-12-07 CN claimed
CN-103556174-B The synthetic method of a kind of 4-chloro-1-methyl-3-ethyl-5-pyrazole carboxylic acid second ester HARBIN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2016-06-01 CN claimed
CN-103360314-B The new preparation process of tebufenpyrad JIANG University OF TECHNOLOGY (CN) 2015-08-05 CN claimed
CN-103351340-B Novel preparation method of tolfenpyrad UNIV ZHEJIANG TECHNOLOGY 2015-01-28 CN claimed
CN-103360314-A New preparation method of tebufenpyrad UNIV ZHEJIANG TECHNOLOGY 2013-10-23 CN claimed
CN-103351340-A Novel preparation method of tolfenpyrad UNIV ZHEJIANG TECHNOLOGY 2013-10-16 CN claimed
CN-101307022-B Green synthetic method for methyl-3-ethyl-4-chlorin-5-pyrazol formyl chloride UNIV ZHEJIANG TECHNOLOGY 2010-12-22 CN claimed
CN-101307022-A Green synthetic method for methyl-3-ethyl-4-chlorin-5-pyrazol formyl chloride UNIV ZHEJIANG TECHNOLOGY (CN) 2008-11-19 CN claimed
CN-121204042-A Method for preparing pesticide intermediate by catalyzing multienzyme and coenzyme co-immobilized nanogel 南京科力硕生物科技有限公司 2025-12-26 CN disclosed
WO-2025055006-A1 MATRINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 成都新朝阳作物科学股份有限公司 2025-03-20 WO disclosed
CN-116063285-B Substituted pyrimidine (thio) ester compound and application thereof 沈阳中化农药化工研发有限公司 2025-02-11 CN disclosed
CN-113512002-B Pyrazole amide compound containing azo structure, and preparation and application thereof 华东理工大学 2024-10-29 CN disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed
EP-0365925-B1 Pyrazole amides and insecticide and miticide containing them as active ingredient MITSUBISHI CHEM CORP (JP) 1995-07-19 EP disclosed
US-5039693-A Pyrazole amides and insecticide and miticide containing them as active ingredient MITSUBISHI KASEI CORPORATION (JP) 1991-08-13 US disclosed
EP-0365925-A1 Pyrazole amides and insecticide and miticide containing them as active ingredient Mitsubishi Chemical Corporation (JP) 1990-05-02 EP disclosed