Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19665269 | 0.74 | MGLL (0.42) | MGLLALDH1A1BLMGMNNLMNA | |
| SCHEMBL28021878 | 0.72 | MGLL (0.41) | MGLLALDH1A1BLMGMNNLMNA | |
| SCHEMBL28674112 | 0.72 | MGLL (0.41) | MGLLALDH1A1BLMGMNNLMNA | |
| SCHEMBL6561912 | 0.72 | ALDH1A1 (0.37) | MGLLALDH1A1BLMGMNNLMNA | |
| SCHEMBL31525220 | 0.70 | AKR1B1 (0.40) | MGLLALDH1A1PTGS1PTGS2SLC22A6 | |
| SCHEMBL31525221 | 0.70 | AKR1B1 (0.40) | MGLLALDH1A1PTGS1PTGS2SLC22A6 | |
| SCHEMBL15941868 | 0.69 | CA12 (0.31) | TP53CA12CA2CA9 | |
| SCHEMBL16500059 | 0.69 | PTGS1 (0.47) | ALDH1A1PTGS1PTGS2SLC22A6SLC22A8 | |
| SCHEMBL28492082 | 0.69 | NFKB1 (0.39) | MGLLALDH1A1BLMGMNNLMNA | |
| SCHEMBL7710571 | 0.68 | KDM4E (0.36) | MGLLCYP1A2CYP2C19PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102597773-B | Reversible covalent linkage of functional molecules | UCL BUSINESS PLC | 2015-07-15 | — | — | CN | disclosed |