Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28022895 | 0.85 | MMP7 (0.40) | — | |
| SCHEMBL28022383 | 0.78 | SFRP1 (0.44) | — | |
| SCHEMBL28159883 | 0.77 | KMT2A (0.54) | — | |
| SCHEMBL28847087 | 0.77 | TSHR (0.54) | — | |
| SCHEMBL28022416 | 0.76 | POLB (0.46) | — | |
| SCHEMBL11684211 | 0.74 | CA2 (0.66) | PTGS2KIF11CA2CA1CA9 | |
| SCHEMBL28022378 | 0.74 | PDK1 (0.39) | CA2CA12 | |
| SCHEMBL1068740 | 0.74 | CA12 (0.50) | PTGS2PTGS1PDPK1KIF11CA2 | |
| Hydrochloric Acid SCHEMBL16015050 | 0.73 | CA12 (0.49) | PTGS2PTGS1PDPK1KIF11CA2 | |
| SCHEMBL9047160 | 0.73 | CA2 (0.56) | PTGS2PTGS1KIF11CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |