SCHEMBL28022591

SCHEMBL28022591

CC(=O)C(c1ccccc1)c1[nH]c2ccccc2c1CCN

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 7/20 0.54
MTNR1B P49286 7/20 0.54
HTR6 P50406 1/20 0.49
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP19A1 P11511 2/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
FOLH1 Q04609 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7749049 0.76 TBXAS1 (0.52) MTNR1AMTNR1BHTR6KDM4EALDH1A1
Oxalic Acid SCHEMBL27171318 0.72 MAPT (0.63) HTR6KDM4EALDH1A1GAAMAPT
SCHEMBL2003146 0.72 KDM4E (0.72) HTR6KDM4EALDH1A1FOLH1
SCHEMBL4490559 0.71 CYP19A1 (0.42) MTNR1AMTNR1BHTR6CYP19A1CHRNB2
SCHEMBL8692157 0.70 HTR6 (0.53) MTNR1AMTNR1BHTR6KDM4EALDH1A1
SCHEMBL5495499 0.69 HTR6 (0.66) HTR6KDM4EALDH1A1GAAFOLH1
Oxalic Acid SCHEMBL274980 0.69 HTR6 (0.51) MTNR1AMTNR1BHTR6KDM4EALDH1A1
SCHEMBL1424220 0.68 ALDH1A1 (0.69) HTR6KDM4EALDH1A1GAAMAPT
SCHEMBL29415611 0.68 ALDH1A1 (0.69) HTR6KDM4EALDH1A1GAAMAPT
SCHEMBL8347063 0.68 HTR6 (0.52) HTR6KDM4EALDH1A1MAPTFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107174586-A Using giantreed alkali derivant as the pharmaceutical composition of active component and its application 中国科学院昆明植物研究所 2017-09-19 CN disclosed
CN-102573496-B Slow release magnesium composition and uses thereof MAGCEUTICS, INC. (US) 2015-08-26 CN disclosed