SCHEMBL28022989

SCHEMBL28022989

COc1c[c]c(C(=N)N)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 3/20 0.52
PRSS2 P07478 3/20 0.52
PRSS3 P35030 3/20 0.52
PTGIR P43119 1/20 0.43
IDO1 P14902 2/20 0.41
NQO2 P16083 2/20 0.40
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
PARP10 Q53GL7 2/20 0.38
PARP1 P09874 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
PARP4 Q9UKK3 1/20 0.38
NOS3 P29474 2/20 0.37
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
HTR3A P46098 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37
CA12 O43570 1/20 0.37
CA7 P43166 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4593743 0.81 CA1 (0.52) PRSS1PRSS2PRSS3CA1CA2
SCHEMBL8755333 0.74 CA1 (0.50) CA1CA2PARP10PARP1PARP2
SCHEMBL3956678 0.74 HPGD (0.43) CA1CA2PARP10PARP1PARP2
SCHEMBL7302208 0.73 CA1 (0.52) CA1CA2PARP10PARP1PARP2
SCHEMBL428892 0.69 PRSS1 (1.00) PRSS1PRSS2PRSS3PTGIRNQO2
SCHEMBL5168543 0.69
SCHEMBL1029610 0.69
SCHEMBL9786928 0.68 CES2 (0.51) CA1CA2MAPK1
Hydrochloric Acid SCHEMBL2570665 0.67 PRSS1 (0.95) PRSS1PRSS2PRSS3PTGIRNQO2
SCHEMBL458125 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104860997-A 2,5-dimethyl thioterephthalic acid bridged bismolybdenum complex, and preparation method thereof and application thereof in molecular devices UNIV JINAN 2015-08-26 CN claimed
CN-104860997-A 2,5-dimethyl thioterephthalic acid bridged bismolybdenum complex, and preparation method thereof and application thereof in molecular devices UNIV JINAN 2015-08-26 CN disclosed