Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | MMP7 | P09237 | 3/20 | 0.44 |
| ▸ | MMP12 | P39900 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023039 | 0.88 | TSHR (0.47) | LMNATSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL3919696 | 0.84 | LMNA (0.48) | LMNATSHRMMP1MMP7MMP12 | |
| SCHEMBL28023655 | 0.78 | TSHR (0.50) | LMNATSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL5725942 | 0.77 | LMNA (0.55) | LMNATSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL2013038 | 0.77 | LMNA (0.55) | LMNATSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL28204939 | 0.76 | L3MBTL1 (0.48) | LMNATSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL7296124 | 0.76 | LMNA (0.53) | LMNATSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL525355 | 0.76 | LMNA (0.53) | LMNATSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL443825 | 0.76 | ALDH1A1 (0.54) | LMNATSHRTP53SMN1; SMN2NPC1 | |
| SCHEMBL16046812 | 0.75 | LMNA (0.40) | LMNATSHRTP53MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509135-B | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-07-22 | — | — | CN | disclosed |