Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297620 | 0.84 | LMNA (0.37) | CASP1TSHRKMT2AALDH1A1KDM4E | |
| SCHEMBL5915755 | 0.78 | LMNA (0.45) | TSHRHCRTR1KMT2ANPC1ALDH1A1 | |
| SCHEMBL28468411 | 0.76 | TSHR (0.43) | TSHRHCRTR1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5694901 | 0.74 | ALDH1A1 (0.42) | TSHRKMT2AALDH1A1LMNAHPGD | |
| SCHEMBL6237542 | 0.74 | TSHR (0.41) | TSHRKMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL8617657 | 0.72 | TSHR (0.41) | CASP1TSHRKMT2ANPC1ALDH1A1 | |
| SCHEMBL8617661 | 0.72 | TSHR (0.41) | CASP1TSHRKMT2ANPC1ALDH1A1 | |
| SCHEMBL6710179 | 0.72 | ALDH1A1 (0.44) | TSHRKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL27478929 | 0.72 | TSHR (0.32) | TSHR | |
| SCHEMBL8463766 | 0.71 | HIF1A (0.35) | TSHRHCRTR1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822678-A | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMA SPA | 2015-08-05 | — | — | CN | disclosed |