Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023133 | 0.84 | CASP1 (0.39) | LMNATSHRKDM4EHSD17B10HPGD | |
| SCHEMBL6237542 | 0.79 | TSHR (0.41) | LMNATSHRKDM4EHSD17B10HPGD | |
| SCHEMBL487252 | 0.77 | ADRA2A (0.34) | LMNATSHRKDM4EHSD17B10HPGD | |
| SCHEMBL27433644 | 0.77 | ALDH1A1 (0.50) | TSHRKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL27473286 | 0.75 | LMNA (0.60) | LMNATSHRKDM4EHSD17B10HPGD | |
| SCHEMBL27761128 | 0.75 | ALDH1A1 (0.41) | LMNATSHRKDM4EHSD17B10HPGD | |
| SCHEMBL1426459 | 0.75 | NPC1 (0.46) | LMNATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL8380942 | 0.75 | IRAK4 (0.49) | LMNATSHRKDM4EHSD17B10HPGD | |
| SCHEMBL6850542 | 0.75 | CTSD (0.57) | LMNATSHRKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL6947591 | 0.74 | ALDH1A1 (0.61) | LMNATSHRKDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232584-B | As 6 inhibitor of histone deacetylase new compound and include its pharmaceutical composition | 株式会社钟根堂 | 2019-06-28 | — | — | CN | disclosed |