Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820942 | 0.91 | L3MBTL1 (0.50) | MAPTHPGDRAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL12789031 | 0.81 | MAPT (0.42) | MAPTRAB9AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4720208 | 0.79 | HPGD (0.46) | MAPTHPGDRAB9AUSP2L3MBTL1 | |
| SCHEMBL28023861 | 0.78 | MEN1 (0.40) | MAPTHPGDRAB9AUSP2L3MBTL1 | |
| SCHEMBL1496782 | 0.75 | LMNA (0.50) | MAPTRAB9AL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL772925 | 0.74 | CA1 (0.45) | MAPTHPGDRAB9AUSP2ALDH1A1 | |
| SCHEMBL15855667 | 0.74 | HPGD (0.49) | MAPTHPGDRAB9AUSP2L3MBTL1 | |
| SCHEMBL28754175 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL18472987 | 0.74 | ALDH1A1 (0.48) | MAPTHPGDRAB9AUSP2L3MBTL1 | |
| SCHEMBL3926773 | 0.74 | ALDH1A1 (0.43) | MAPTALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744325-B | A kind of Alpha-hydroxy thioether and preparation method and application | 中国人民大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-104744325-A | Alpha- hydroxysulfide and preparation method and application thereof | PEOPLES UNIV CHINA | 2015-07-01 | — | — | CN | disclosed |