SCHEMBL28023915

SCHEMBL28023915

COC(=O)CCC(C(=O)O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 8/20 0.47
PTGS1 P23219 1/20 0.43
GAA P10253 3/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GLRA3 O75311 1/20 0.39
GLRB P48167 1/20 0.39
KMT2A Q03164 1/20 0.38
GPR55 Q9Y2T6 1/20 0.38
SLC1A1 P43005 1/20 0.37
LMNA P02545 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28114687 0.89 VCAM1 (0.47) VCAM1PTGS1GAACA1CA2
SCHEMBL28049859 0.87 VCAM1 (0.47) VCAM1PTGS1GAACA1CA2
SCHEMBL1278397 0.82 LMNA (0.44) GAACA1CA2ALDH1A1TDP1
SCHEMBL27475122 0.81 VCAM1 (0.45) VCAM1PTGS1GAACA1CA2
SCHEMBL1278249 0.79 LMNA (0.46) PTGS1GAACA1CA2ALDH1A1
SCHEMBL11782511 0.78 VCAM1 (0.45) VCAM1PTGS1GAACA1CA2
SCHEMBL11778178 0.77 ALDH1A1 (0.45) VCAM1GAACA1CA2ALDH1A1
SCHEMBL2542322 0.77 GPR84 (0.40) GAACA1CA2ALDH1A1TDP1
SCHEMBL11728968 0.77 GPR84 (0.40) GAACA1CA2ALDH1A1TDP1
SCHEMBL39475 0.77 GPR84 (0.40) GAACA1CA2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104817435-A Method for preparing 2, 6-di-tert-butylphenol from recovered waste YINGKOU FENGGUANG CHEMICAL CO LTD 2015-08-05 CN disclosed