SCHEMBL28049859

SCHEMBL28049859

CC(C)(C)c1cc(C(CCC(=O)O)C(=O)O)cc(C(C)(C)C)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 4/20 0.47
GLRA3 O75311 1/20 0.46
GLRB P48167 1/20 0.46
GPR55 Q9Y2T6 1/20 0.40
GAA P10253 3/20 0.40
CA2 P00918 2/20 0.40
CA1 P00915 1/20 0.40
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 1/20 0.39
TYR P14679 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP2C9 P11712 1/20 0.39
HSD17B10 Q99714 1/20 0.39
GABBR2 O75899 1/20 0.39
GABBR1 Q9UBS5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27475122 0.91 VCAM1 (0.45) VCAM1GLRA3GLRBGPR55GAA
SCHEMBL28023915 0.87 VCAM1 (0.47) VCAM1GLRA3GLRBGPR55GAA
SCHEMBL1278397 0.86 LMNA (0.44) GLRA3GLRBGPR55GAACA2
SCHEMBL11778178 0.84 ALDH1A1 (0.45) VCAM1GLRA3GLRBGPR55GAA
SCHEMBL1278249 0.82 LMNA (0.46) GLRA3GLRBGAACA2CA1
SCHEMBL11728968 0.81 GPR84 (0.40) GLRA3GLRBGAACA2CA1
SCHEMBL39475 0.81 GPR84 (0.40) GLRA3GLRBGAACA2CA1
SCHEMBL8419030 0.81 GPR84 (0.40) GLRA3GLRBGAACA2CA1
SCHEMBL2542322 0.81 GPR84 (0.40) GLRA3GLRBGAACA2CA1
SCHEMBL11739834 0.81 GPR84 (0.40) GLRA3GLRBGAACA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104817435-B Method for preparing 2, 6-di-tert-butylphenol from recovered waste 营口市风光化工有限公司 2017-01-11 CN claimed
CN-105601518-A Sterically hindered hydroxyphenylcarboxylic acid esters, preparation method thereof and application thereof NINGBO INST MAT TECH & ENG CAS 2016-05-25 CN disclosed