Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MARS1 | P56192 | 3/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677861 | 0.96 | CYP1A2 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19MARS1 | |
| SCHEMBL27677824 | 0.96 | MARS1 (0.46) | CYP1A2CYP3A4CYP2C9CYP2C19MARS1 | |
| SCHEMBL28024007 | 0.91 | MAPT (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19MARS1 | |
| SCHEMBL27687135 | 0.76 | MARS1 (0.65) | CYP1A2CYP2C9MARS1KMT2ALMNA | |
| SCHEMBL27706388 | 0.73 | GRN (0.56) | CYP1A2CYP2C9MARS1KMT2ALMNA | |
| SCHEMBL7901219 | 0.71 | MAPT (0.59) | MARS1SMN1; SMN2 | |
| SCHEMBL28760198 | 0.71 | MARS1 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19MARS1 | |
| SCHEMBL30406016 | 0.71 | HDAC6 (0.44) | MARS1KMT2AMEN1CA12 | |
| SCHEMBL6938286 | 0.69 | CYP1A2 (0.63) | CYP1A2KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL18821435 | 0.69 | CYP1A2 (0.76) | CYP1A2CYP3A4CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1958589-A | 6 (aryloxy methyl) - 2 aryl - 6, 7 dihydro 4H - pyrido [5,1 c ] [1,4] oxaxine - 4 - ketone derivative, and preparation method | UNIV SHANDONG (CN) | 2007-05-09 | — | — | CN | disclosed |