Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677861 | 0.96 | CYP1A2 (0.46) | MARS1CYP1A2CACNA1GKCNH2LMNA | |
| SCHEMBL28760197 | 0.96 | CYP1A2 (0.49) | MARS1CYP1A2LMNAMAPK1RECQL | |
| SCHEMBL28024007 | 0.95 | MAPT (0.48) | MARS1CYP1A2LMNAMAPK1CYP3A4 | |
| SCHEMBL27687135 | 0.73 | MARS1 (0.65) | MARS1CYP1A2LMNAMAPK1CYP2C9 | |
| SCHEMBL30406016 | 0.72 | HDAC6 (0.44) | MARS1KMT2AMEN1 | |
| SCHEMBL7901219 | 0.71 | MAPT (0.59) | MARS1SMN1; SMN2 | |
| SCHEMBL27706388 | 0.70 | GRN (0.56) | MARS1CYP1A2LMNAMAPK1TSHR | |
| SCHEMBL8367181 | 0.70 | MARS1 (0.65) | MARS1CYP1A2LMNATSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL8364783 | 0.69 | MARS1 (0.64) | MARS1CYP1A2LMNATSHRCYP3A4 | |
| SCHEMBL11546333 | 0.69 | CYP1A2 (0.65) | CYP1A2LMNAMAPK1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1958589-A | 6 (aryloxy methyl) - 2 aryl - 6, 7 dihydro 4H - pyrido [5,1 c ] [1,4] oxaxine - 4 - ketone derivative, and preparation method | UNIV SHANDONG (CN) | 2007-05-09 | — | — | CN | disclosed |