Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 10/20 | 0.48 |
| ▸ | CDK8 | P49336 | 10/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024769 | 0.83 | CCNC (0.44) | CCNCCDK8PIM1 | |
| SCHEMBL28821388 | 0.82 | CCNC (0.44) | CCNCCDK8PIM1 | |
| SCHEMBL15741758 | 0.79 | CCNC (0.46) | CCNCCDK8PIM1 | |
| SCHEMBL28024785 | 0.79 | CCNC (0.43) | CCNCCDK8PIM1DGAT1ADORA3 | |
| SCHEMBL28024329 | 0.78 | CCNC (0.43) | CCNCCDK8PIM1TSHRGRM2 | |
| SCHEMBL1319809 | 0.74 | CCNC (0.49) | CCNCCDK8PIM1ADORA3TSHR | |
| SCHEMBL28148153 | 0.73 | PDE10A (0.44) | CCNCCDK8GRM2 | |
| SCHEMBL4580346 | 0.73 | CCNC (0.64) | CCNCCDK8PIM1PIM2 | |
| SCHEMBL4729623 | 0.72 | P2RX7 (0.44) | CCNCCDK8ADORA3KMT2A | |
| SCHEMBL4579667 | 0.72 | CCNC (0.45) | CCNCCDK8PIM1DGAT1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812387-A | Substituted 1, 6-naphthyridines | HOFFMANN LA ROCHE | 2015-07-29 | — | — | CN | disclosed |