Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025183 | 0.80 | KCNMA1 (0.36) | PIK3CDPIK3CANUDT1NPC1PDE4D | |
| SCHEMBL27866878 | 0.74 | GRIN2D (0.40) | PIK3CDPIK3CAL3MBTL1ATRMTOR | |
| SCHEMBL28025174 | 0.71 | CHRNB2 (0.41) | ATRMTORPIK3C3HTT | |
| SCHEMBL30206003 | 0.70 | AKR1C3 (0.46) | ALDH1A1KDM4EGAA | |
| SCHEMBL28024733 | 0.70 | POLB (0.35) | PIK3CDPIK3CANUDT1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28025203 | 0.69 | ATR (0.35) | ATRPIK3C3ALDH1A1KDM4E | |
| SCHEMBL137068 | 0.68 | LMNA (0.47) | PIK3C3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18988810 | 0.67 | OPRL1 (0.36) | PIK3CDPIK3CANUDT1PDE4DATR | |
| SCHEMBL2096944 | 0.63 | PIM1 (0.50) | NPC1L3MBTL1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28821284 | 0.62 | MTOR (0.36) | PIK3CAATRMTORPIK3C3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143209-A | Biaryl amide compounds as kinase inhibitors | NOVARTIS AG | 2015-12-09 | — | — | CN | disclosed |