Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601087 | 0.83 | AR (0.50) | ARMAPTTDP1THRBPTGS2 | |
| SCHEMBL8400694 | 0.83 | AR (0.50) | ARMAPTTDP1THRBPTGS2 | |
| SCHEMBL27652067 | 0.79 | AR (0.44) | ARMAPTTDP1THRBPTGS2 | |
| SCHEMBL8519336 | 0.79 | PTGS2 (0.48) | ARMAPTTDP1THRBPTGS2 | |
| SCHEMBL2980868 | 0.77 | PTGS2 (0.49) | ARPTGS2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL5983793 | 0.77 | PTGS2 (0.49) | ARPTGS2ALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL27976467 | 0.77 | CYP1A2 (0.40) | ARPGR | |
| SCHEMBL28096615 | 0.75 | AR (0.60) | ARMAPTTDP1THRBALDH1A1 | |
| SCHEMBL27613330 | 0.75 | MEN1 (0.42) | ARMAPTTDP1THRBPTGS2 | |
| SCHEMBL9644566 | 0.74 | MEN1 (0.44) | ARMAPTTHRBPTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803916-B | Hete rocyclic derivatives as SARM (SARMS) | 詹森药业有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-104803916-A | Novel heterocycle derivatives useful as selective androgen receptor modulators (sarms) | JANSSEN PHARMACEUTICA NV | 2015-07-29 | — | — | CN | disclosed |