Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 3/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201706 | 0.83 | HSPB1 (0.46) | PTPRCS100A4MEN1KMT2APTGS2 | |
| SCHEMBL10508753 | 0.83 | PTGS2 (0.55) | PTPRCS100A4MEN1KMT2APTGS2 | |
| SCHEMBL27607560 | 0.81 | GPR35 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2329450 | 0.76 | POLB (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27906245 | 0.75 | KMT2A (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8354258 | 0.74 | ALDH1A1 (0.47) | PTPRCS100A4POLBALDH1A1CYP3A4 | |
| SCHEMBL85535 | 0.73 | MEN1 (0.64) | MEN1KMT2APOLBMAPTNPC1 | |
| SCHEMBL28122065 | 0.72 | PTPRC (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11822059 | 0.72 | TSHR (0.52) | PTPRCS100A4ALDH1A1CYP3A4TDP1 | |
| SCHEMBL2818370 | 0.72 | ALDH1A1 (0.50) | PTPRCS100A4MEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391601-A1 | SULFAMOYL- PHENYL-UREIDO BENZAMIDINE-DERIVATIVES AS ANTIMALARIAL AGENTS | 4SC AG (DE) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010086177-A1 | SULFAMOYL- PHENYL-UREIDO BENZAMIDINE-DERIVATIVES AS ANTIMALARIAL AGENTS | 4SC AG (DE) | 2010-08-05 | — | — | WO | disclosed |