SCHEMBL28025473

SCHEMBL28025473

Fc1cccc(F)c1C1=C[CH]c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
AKR1A1 P14550 1/20 0.32
AKR1B1 P15121 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17293173 0.82
SCHEMBL5824297 0.78 MEN1 (0.32)
SCHEMBL28907130 0.76 MYC (0.39) PDK2CA1CA2CA7CA9
SCHEMBL28515923 0.72 GPR3 (0.38) PDK2
SCHEMBL5076754 0.70 ALDH1A1 (0.41)
SCHEMBL7644097 0.68 PTPN1 (0.44) CA1CA2CA9
SCHEMBL22129686 0.67 CA1 (0.48) PDK2CA1CA2CA7CA9
SCHEMBL28515390 0.67 NPC1 (0.38) CA1CA2CA7CA9
SCHEMBL28521719 0.67 HSD11B1 (0.41) PDK2
SCHEMBL28521495 0.67 TRPA1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN claimed
CN-108137729-B Catalysts for forming multimodal polymers 埃克森美孚化学专利公司 2021-02-05 CN disclosed
CN-109824802-A Metallocenic compound, catalyst system and the polymerization using them of bridging 埃克森美孚化学专利公司 2019-05-31 CN disclosed
CN-108137729-A It is used to form the catalyst of multimodal polymer 埃克森美孚化学专利公司 2018-06-08 CN disclosed
CN-104822697-A Bridged metallocene compounds, catalyst systems and polymerization processes using the same EXXONMOBIL CHEM PATENTS INC 2015-08-05 CN disclosed