Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770094 | 0.83 | LMNA (0.43) | HTTKMT2AMEN1MAPTLMNA | |
| SCHEMBL27703769 | 0.83 | MAPT (0.49) | HTTKMT2AMEN1MAPTLMNA | |
| SCHEMBL27615544 | 0.83 | MAPT (0.43) | HTTKMT2AMEN1GRM5ENPP2 | |
| SCHEMBL27868027 | 0.81 | MAPT (0.60) | KMT2AMEN1MAPTLMNAMAPK1 | |
| SCHEMBL27737427 | 0.81 | MAPT (0.42) | KMT2AMEN1MAPTLMNAMAPK1 | |
| SCHEMBL28752031 | 0.81 | ALDH1A1 (0.69) | HTTKMT2AMEN1MAPTLMNA | |
| SCHEMBL30998112 | 0.81 | MAPT (0.63) | HTTKMT2AHSD11B1GRM5ENPP2 | |
| SCHEMBL4435451 | 0.81 | MAPT (0.63) | HTTKMT2AHSD11B1GRM5ENPP2 | |
| SCHEMBL27790950 | 0.79 | ADRA2C (0.51) | KMT2AMEN1MAPTLMNAMAPK1 | |
| SCHEMBL27697694 | 0.79 | MEN1 (0.40) | HTTKMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844573-A | Miazines BTK inhibitor, preparation method and medical application thereof | UNIV CHINA PHARMA | 2015-08-19 | — | — | CN | disclosed |