Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 3/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025979 | 0.77 | ALDH1A1 (0.41) | ALDH1A1ACHEPKMGAAHTT | |
| SCHEMBL28025951 | 0.74 | CYP2A6 (0.44) | ALDH1A1ACHEPKMMEN1KMT2A | |
| SCHEMBL28219823 | 0.70 | NAT1 (0.39) | NAT1ALDH1A1PKMGAAMEN1 | |
| SCHEMBL28051267 | 0.70 | IMPDH2 (0.47) | NAT1IMPDH2ALDH1A1ACHEPKM | |
| SCHEMBL28025428 | 0.69 | GSTP1 (0.47) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL28025431 | 0.68 | CYP2A6 (0.45) | ALDH1A1HTTHSD17B10MAPTALOX15 | |
| SCHEMBL395258 | 0.66 | ALDH1A1 (0.54) | NAT1IMPDH2ALDH1A1ACHEGAA | |
| SCHEMBL5781695 | 0.65 | IMPDH2 (0.48) | NAT1IMPDH2ALDH1A1MEN1KMT2A | |
| SCHEMBL714807 | 0.64 | ALDH1A1 (0.42) | ALDH1A1GAAHSD17B10KDM4EPOLB | |
| SCHEMBL61525 | 0.64 | MEN1 (0.39) | ALDH1A1ACHEPKMGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824802-A | Metallocenic compound, catalyst system and the polymerization using them of bridging | 埃克森美孚化学专利公司 | 2019-05-31 | — | — | CN | claimed |
| CN-108137729-B | Catalysts for forming multimodal polymers | 埃克森美孚化学专利公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-109824802-A | Metallocenic compound, catalyst system and the polymerization using them of bridging | 埃克森美孚化学专利公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-108137729-A | It is used to form the catalyst of multimodal polymer | 埃克森美孚化学专利公司 | 2018-06-08 | — | — | CN | disclosed |