SCHEMBL28026665

SCHEMBL28026665

CCC(C)(C)C(=O)Oc1ccccc1C(=O)OC(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.48
NPC1 O15118 1/20 0.46
PTGS2 P35354 1/20 0.41
PDK2 Q15119 1/20 0.41
KDM4E B2RXH2 4/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 2/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HPGD P15428 2/20 0.38
XBP1 P17861 1/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
IRAK4 Q9NWZ3 1/20 0.38
PDCD1 Q15116 1/20 0.38
CD274 Q9NZQ7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28026640 0.87 KDM4E (0.45) ELANENPC1PTGS2PDK2KDM4E
SCHEMBL28026627 0.86 KDM4E (0.44) ELANENPC1PTGS2PDK2KDM4E
SCHEMBL6722003 0.84 ELANE (0.54) ELANEPTGS2KDM4EMEN1RECQL
SCHEMBL825371 0.82 HSD17B10 (0.51) ELANEPTGS2KDM4EKMT2AHSD17B10
SCHEMBL28026634 0.81 NPC1 (0.49) ELANENPC1PTGS2PDK2KDM4E
SCHEMBL28213186 0.81 KDM4E (0.57) ELANEPTGS2KDM4EMEN1RECQL
SCHEMBL28026636 0.81 NPC1 (0.51) NPC1PTGS2PDK2KDM4EMEN1
SCHEMBL28026655 0.81 ALDH1A1 (0.59) ELANEPTGS2PDK2HSD17B10LMNA
SCHEMBL1283020 0.79 NPC1 (0.55) ELANENPC1PTGS2PDK2KDM4E
SCHEMBL28026649 0.78 TSHR (0.61) ELANEPTGS2KDM4EMEN1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829757-B A kind of ingredient of solid catalyst of olefin polymerization acid esters compound containing bigcatkin willow and its preparation method and application 中国科学院化学研究所 2018-04-27 CN disclosed
CN-104829757-A Salicylate-compound-containing solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed