Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.50 |
| ▸ | HTR6 | P50406 | 10/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000134 | 0.88 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAADRB1HTR6 | |
| SCHEMBL28027579 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNAHTR6CA12 | |
| Hydrochloric Acid SCHEMBL11534183 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNACA12CA1CA2 | |
| SCHEMBL8090756 | 0.81 | HTR6 (0.63) | HTR6HTR7HTR3EHTR3BHTR3A | |
| SCHEMBL3923062 | 0.79 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAHTR6CA12 | |
| SCHEMBL28153181 | 0.75 | MAPT (0.75) | ALDH1A1KDM4ELMNACA12CA1 | |
| SCHEMBL29805912 | 0.75 | HTR1A (0.62) | ADRB1HTR6HTR7HTR3A | |
| SCHEMBL255418 | 0.75 | HTR1A (0.62) | ADRB1HTR6HTR7HTR3A | |
| SCHEMBL4518266 | 0.74 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNAADRB1HTR6 | |
| Hydrochloric Acid SCHEMBL2959720 | 0.74 | HTR1A (0.65) | ADRB1HTR6HTR7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102459197-B | Be applicable to treatment response thrombotonin 5-HT 6n-phenyl-(piperazinyl or homopiperazine the base)-benzsulfamide of the illness of the adjustment of acceptor or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compound | ABBVIE (US) | 2015-08-19 | — | — | CN | claimed |
| CN-102459197-B | Be applicable to treatment response thrombotonin 5-HT 6n-phenyl-(piperazinyl or homopiperazine the base)-benzsulfamide of the illness of the adjustment of acceptor or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compound | ABBVIE (US) | 2015-08-19 | — | — | CN | disclosed |