Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 3/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028172 | 0.85 | MEN1 (0.41) | CTSDPSMB5MMP1REN | |
| SCHEMBL28027550 | 0.84 | REN (0.40) | CTSDPSMB5MMP1MMEREN | |
| SCHEMBL28821803 | 0.83 | MEN1 (0.44) | CTSD | |
| SCHEMBL28028183 | 0.81 | PSMB5 (0.37) | CTSDPSMB5MMP1RENHSP90AA1 | |
| SCHEMBL15299885 | 0.72 | MEN1 (0.47) | CTSDPSMB5REN | |
| SCHEMBL5707491 | 0.70 | PSMB1 (0.47) | PSMB5MMEREN | |
| SCHEMBL21458026 | 0.66 | MEN1 (0.46) | REN | |
| SCHEMBL21457988 | 0.66 | CAPN1 (0.64) | PSMB5MMP1 | |
| SCHEMBL28582996 | 0.65 | CYP3A4 (0.48) | CTSDPSMB5MMP1MMP3REN | |
| SCHEMBL28582992 | 0.65 | CYP3A4 (0.48) | CTSDPSMB5MMP1MMP3REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282043-B | Congenital agyria therapeutic agent | OSAKA CITY UNIVERSITY (JP) | 2015-09-30 | — | — | CN | disclosed |