Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28028262 | 1.00 | MMP13 (0.59) | MMP13HDAC2GUSBMEN1KMT2A | |
| SCHEMBL28028260 | 0.87 | MAOA (0.58) | HDAC2GUSBMEN1KMT2APOLB | |
| SCHEMBL28028263 | 0.87 | MAOA (0.58) | HDAC2GUSBMEN1KMT2APOLB | |
| SCHEMBL28028735 | 0.80 | MMP13 (0.66) | MMP13HDAC2MEN1KMT2APOLB | |
| SCHEMBL3027767 | 0.76 | MMP13 (0.67) | MMP13KMT2APOLBKDM4EMAPT | |
| SCHEMBL28028264 | 0.75 | KMT2A (0.74) | MEN1KMT2APOLBATMNPC1 | |
| SCHEMBL28028265 | 0.75 | KMT2A (0.74) | MEN1KMT2APOLBATMNPC1 | |
| SCHEMBL6514040 | 0.74 | MMP13 (1.00) | MMP13MEN1KMT2AATMNPC1 | |
| SCHEMBL28229577 | 0.72 | TP53 (0.56) | MMP13HDAC2KMT2APOLBNPC1 | |
| SCHEMBL6015700 | 0.70 | MAOB (0.67) | MMP13MEN1KMT2ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860866-B | 5- (substitution carbon acylamino) -1H- indoles -2- carbohydrazide derivatives and its preparation method and application | 厦门大学 | 2018-07-17 | — | — | CN | disclosed |
| CN-104860866-A | 5-(substituted carbonylamino)-1H-indole-2-carbohydrazide derivatives as well as preparation method and application thereof | UNIV XIAMEN | 2015-08-26 | — | — | CN | disclosed |