Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PLD2 | O14939 | 1/20 | 0.48 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.48 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3027767 | 0.84 | MMP13 (0.67) | MMP13KDM4EALDH1A1KMT2AROCK2 | |
| SCHEMBL28028254 | 0.82 | MAOA (0.66) | KDM4EGAAALDH1A1MAPK1HDAC2 | |
| SCHEMBL22718557 | 0.81 | PLD2 (0.56) | KDM4EGAAALDH1A1MAPK1HDAC2 | |
| SCHEMBL28229577 | 0.80 | TP53 (0.56) | MMP13KDM4EHDAC2KMT2ANPC1 | |
| SCHEMBL28028262 | 0.80 | MMP13 (0.59) | MMP13KDM4EGAAHDAC2KMT2A | |
| SCHEMBL28028261 | 0.80 | MMP13 (0.59) | MMP13KDM4EGAAHDAC2KMT2A | |
| SCHEMBL6514040 | 0.80 | MMP13 (1.00) | MMP13KDM4EGAAALDH1A1KMT2A | |
| SCHEMBL15746114 | 0.79 | PIN1 (0.66) | KDM4EGAAALDH1A1MAPK1HDAC2 | |
| SCHEMBL27520204 | 0.78 | NPC1 (0.53) | MMP13ALDH1A1MAPK1HDAC2KMT2A | |
| SCHEMBL6015700 | 0.77 | MAOB (0.67) | MMP13KDM4EALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860866-B | 5- (substitution carbon acylamino) -1H- indoles -2- carbohydrazide derivatives and its preparation method and application | 厦门大学 | 2018-07-17 | — | — | CN | disclosed |
| CN-104860866-A | 5-(substituted carbonylamino)-1H-indole-2-carbohydrazide derivatives as well as preparation method and application thereof | UNIV XIAMEN | 2015-08-26 | — | — | CN | disclosed |