Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27619537 | 0.80 | PARP1 (0.46) | CA1CA2P2RX1P2RX4P2RX7 | |
| SCHEMBL27582539 | 0.80 | P2RX1 (0.54) | CA1CA2P2RX1P2RX4P2RX7 | |
| SCHEMBL28029365 | 0.80 | CA1 (0.49) | CA1CA2P2RX1P2RX4P2RX7 | |
| SCHEMBL28029031 | 0.75 | AR (0.50) | CA1CA2P2RX1MAPTKDM4E | |
| SCHEMBL28821920 | 0.75 | CA1 (0.44) | CA1CA2P2RX1P2RX4P2RX7 | |
| SCHEMBL28029364 | 0.75 | ALDH1A1 (0.45) | CA1CA2P2RX1P2RX4P2RX7 | |
| SCHEMBL28029023 | 0.75 | KLKB1 (0.44) | CA1CA2P2RX1P2RX4P2RX7 | |
| SCHEMBL28029025 | 0.75 | LMNA (0.52) | CA1CA2P2RX1P2RX4P2RX7 | |
| SCHEMBL28821963 | 0.74 | CA1 (0.43) | CA1CA2P2RX1P2RX4P2RX7 | |
| SCHEMBL28105012 | 0.74 | TMPRSS4 (0.55) | CA1CA2P2RX1P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | claimed |
| CN-104771386-A | Benzamide compound and applications thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-07-15 | — | — | CN | disclosed |