Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843587 | 0.86 | KMT2A (0.49) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL3480009 | 0.84 | ALDH1A1 (0.54) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL2001002 | 0.82 | HSD11B1 (0.53) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL5702524 | 0.81 | HSD17B10 (0.41) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL28814954 | 0.80 | HSD11B1 (0.51) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL31683755 | 0.80 | HSD11B1 (0.56) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL29497718 | 0.80 | MAPT (0.48) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL6938262 | 0.80 | MAPT (0.48) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL5673580 | 0.80 | MEN1 (0.57) | KMT2AMEN1ESR1ESR2GAA | |
| SCHEMBL9957659 | 0.78 | KMT2A (0.44) | KMT2AMEN1GAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008378-A | Reaction catalyst for cross coupling and method for manufacturing aromatic compound | HOKKO CHEM IND CO | 2015-10-28 | — | — | CN | disclosed |