SCHEMBL28030816

SCHEMBL28030816

NCc1ccccc1-c1cccc2c1C=C[CH]2

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.46
PNMT P11086 3/20 0.38
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30
CSNK2A3 Q8NEV1 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041352 0.94 DPP4 (0.45) DPP4PNMTCSNK2A2CSNK2BCSNK2A1
SCHEMBL6652215 0.83 CSNK2A2 (0.36) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL6650445 0.80 NR1H2 (0.31)
SCHEMBL6648232 0.79 GABRA1 (0.41)
SCHEMBL6650685 0.78 NR1H2 (0.38)
SCHEMBL28030819 0.76 HRH3 (0.43) DPP4CSNK2A1LOXL2
SCHEMBL3787333 0.74 DPP4 (0.73) DPP4PNMTCSNK2A2CSNK2BCSNK2A1
SCHEMBL6649547 0.73 HTR7 (0.35)
SCHEMBL6649333 0.73 PTGS2 (0.36) DPP4
SCHEMBL28148805 0.72 HTR7 (0.39) PNMTCSNK2A1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105008408-B METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER 日本聚乙烯株式会社 2017-05-10 CN disclosed
CN-105026408-A Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORP 2015-11-04 CN disclosed
CN-105008408-A METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP 2015-10-28 CN disclosed