SCHEMBL6652215

SCHEMBL6652215

CCc1ccccc1-c1cccc2c1C=C[CH]2

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A1 P68400 1/20 0.36
CSNK2A3 Q8NEV1 1/20 0.36
GABRA1 P14867 3/20 0.35
GABRB2 P47870 3/20 0.35
CYP2D6 P10635 1/20 0.33
MGLL Q99685 1/20 0.33
PDK2 Q15119 1/20 0.33
DHFR P00374 1/20 0.32
KCNN4 O15554 1/20 0.31
TRPA1 O75762 1/20 0.31
LMNA P02545 1/20 0.30
S1PR5 Q9H228 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6650445 0.87 NR1H2 (0.31)
SCHEMBL6650685 0.84 NR1H2 (0.38) CYP2D6
SCHEMBL1071199 0.83 GABRA1 (0.41) GABRA1GABRB2MGLLPDK2
SCHEMBL28030816 0.83 DPP4 (0.46) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL6648232 0.82 GABRA1 (0.41) GABRA1GABRB2
SCHEMBL28041352 0.78 DPP4 (0.45) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL6649547 0.77 HTR7 (0.35) CYP2D6
SCHEMBL6651510 0.74 TSHR (0.42)
SCHEMBL198461 0.74 CSNK2A2 (0.52) CSNK2A2CSNK2BCSNK2A1CSNK2A3GABRA1
SCHEMBL6649333 0.73 PTGS2 (0.36) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105008408-B METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER 日本聚乙烯株式会社 2017-05-10 CN disclosed
CN-105026408-A Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORP 2015-11-04 CN disclosed
CN-105008408-A METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP 2015-10-28 CN disclosed
EP-1421090-A2 METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM Exxonmobil Chemical Patents Inc. (US) 2004-05-26 EP disclosed
WO-2003002583-A2 METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-01-09 WO disclosed