SCHEMBL28041352

SCHEMBL28041352

Cl[Hf]Cl.NCc1ccccc1-c1cccc2c1C=C[CH]2

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.45
PNMT P11086 3/20 0.34
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
CSNK2A1 P68400 1/20 0.31
CSNK2A3 Q8NEV1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28030816 0.94 DPP4 (0.46) DPP4PNMTCSNK2A2CSNK2BCSNK2A1
SCHEMBL6652215 0.78 CSNK2A2 (0.36) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL27462619 0.76 CYP2A6 (0.36)
SCHEMBL28041357 0.75 PNMT (0.37) PNMTCSNK2BCSNK2A1
SCHEMBL6650445 0.75 NR1H2 (0.31)
SCHEMBL6648232 0.74 GABRA1 (0.41)
SCHEMBL6650685 0.73 NR1H2 (0.38)
SCHEMBL28030819 0.71 HRH3 (0.43) DPP4CSNK2A1
SCHEMBL3787333 0.70 DPP4 (0.73) DPP4PNMTCSNK2A2CSNK2BCSNK2A1
SCHEMBL6649333 0.68 PTGS2 (0.36) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105026408-A Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORP 2015-11-04 CN disclosed