SCHEMBL28031452

SCHEMBL28031452

O=C1C(=O)N(F)c2ccc([N+](=O)[O-])cc21

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 3/20 0.67
CASP1 P29466 2/20 0.67
CASP4 P49662 2/20 0.67
CASP7 P55210 2/20 0.67
CASP9 P55211 2/20 0.67
CASP6 P55212 2/20 0.67
CASP8 Q14790 1/20 0.56
PTPRC P08575 3/20 0.53
S100A4 P26447 2/20 0.53
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA12 O43570 4/20 0.48
CA9 Q16790 3/20 0.48
BCHE P06276 1/20 0.47
ACHE P22303 1/20 0.47
CES1 P23141 1/20 0.47
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
IDO1 P14902 2/20 0.46
CAPN9 O14815 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3594484 0.80 CASP3 (1.00) CASP3CASP1CASP4CASP7CASP9
SCHEMBL30232255 0.80 CASP3 (1.00) CASP3CASP1CASP4CASP7CASP9
SCHEMBL19674180 0.77 PTPRC (0.63) CASP3CASP1CASP4CASP7CASP9
SCHEMBL30819846 0.76 CASP3 (0.66) CASP3CASP1CASP4CASP7CASP9
SCHEMBL21774731 0.76 CASP1 (0.67) CASP3CASP1CASP4CASP7CASP9
SCHEMBL23250129 0.76 CASP3 (0.66) CASP3CASP1CASP4CASP7CASP9
SCHEMBL4625604 0.76 CASP3 (0.67) CASP3CASP1CASP4CASP7CASP9
SCHEMBL26621576 0.76 CASP3 (0.62) CASP3CASP1CASP4CASP7CASP9
SCHEMBL19032766 0.75 CASP1 (0.64) CASP3CASP1CASP4CASP7CASP9
SCHEMBL9330569 0.75 CASP1 (0.61) CASP3CASP1CASP4CASP7CASP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104870422-B Amine derivative or its salt 富士胶片富山化学株式会社 2019-03-15 CN disclosed
CN-104870422-A Novel amine derivative or salt thereof TOYAMA CHEMICAL CO LTD 2015-08-26 CN disclosed