Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30568155 | 0.76 | ACHE (0.42) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL5599308 | 0.76 | ACHE (0.42) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL6062006 | 0.75 | BCHE (0.35) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL28827229 | 0.75 | BCHE (0.32) | BCHEACHE | |
| SCHEMBL2803235 | 0.75 | NPC1 (0.30) | NPC1TP53TSHRRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2805340 | 0.74 | HTR6 (0.33) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL28375726 | 0.74 | HTR6 (0.33) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL28827235 | 0.71 | HTR6 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6062220 | 0.71 | KDM4E (0.31) | TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3627628 | 0.69 | GPR3 (0.34) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253648-A1 | POLYOLEFIN GRAFT COPOLYMER AND ADHESIVE COMPOSITION | Idemitsu Kosan Co., Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |