Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450221 | 0.82 | HDAC6 (0.65) | SMN1; SMN2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL15219379 | 0.81 | KDM4E (0.43) | SMN1; SMN2KDM4EALDH1A1POLBMAPT | |
| SCHEMBL634980 | 0.78 | ALDH1A1 (0.64) | SMN1; SMN2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27894277 | 0.77 | AGBL2 (0.50) | KDM4E | |
| SCHEMBL16424551 | 0.76 | LMNA (0.51) | SMN1; SMN2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL28504409 | 0.76 | GABRR1 (0.44) | SMN1; SMN2KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL3735430 | 0.74 | LMNA (0.53) | SMN1; SMN2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10484494 | 0.74 | GABRR1 (0.42) | SMN1; SMN2KDM4EALDH1A1POLBL3MBTL1 | |
| SCHEMBL24597657 | 0.74 | KDM4E (0.67) | SMN1; SMN2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL4355754 | 0.72 | LMNA (0.56) | SMN1; SMN2KDM4EALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105061338-A | 3-methyl-quinoxaline-2-carboxylic acid chemical synthesis method based on ionic liquid system | PINGYUAN WEIFENG YONGZHU TECHNOLOGY CO LTD | 2015-11-18 | — | — | CN | disclosed |