Sugi Predict

Sugi Predict / Compounds / SCHEMBL10272804

SCHEMBL10272804

SCHEMBL10272804

CCC(CC)C1CCNCC1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ CPN1 P15169 1/20 0.38
▸ CPB2 Q96IY4 1/20 0.38
▸ SHBG P04278 2/20 0.33
▸ KCNH2 Q12809 1/20 0.33
▸ SLC6A2 P23975 10/20 0.33
▸ SLC6A4 P31645 10/20 0.33
▸ SLC6A3 Q01959 10/20 0.33
▸ GNAI3 P08754 4/20 0.32
▸ GNAO1 P09471 4/20 0.32
▸ GNAI1 P63096 4/20 0.32
▸ DPP4 P27487 1/20 0.32
▸ OPRD1 P41143 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13259736 0.86 CPN1 (0.33) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL25527217 0.86 CPN1 (0.46) CPN1CPB2
SCHEMBL21919470 0.86 CPN1 (0.37) CPN1CPB2SHBGSLC6A2SLC6A4
SCHEMBL22264537 0.85 KCNH2 (0.40) CPN1CPB2SHBGKCNH2SLC6A2
SCHEMBL20935045 0.83 CPN1 (0.32) CPN1CPB2DPP4
SCHEMBL13825689 0.83 GNAO1 (0.38) CPN1CPB2GNAI3GNAO1GNAI1
SCHEMBL13349503 0.83 CPN1 (0.32) CPN1CPB2
SCHEMBL31458641 0.81 GNAO1 (0.36) CPN1CPB2GNAI3GNAO1GNAI1
SCHEMBL8436215 0.80 CPN1 (0.35) CPN1CPB2KCNH2SLC6A2SLC6A4
SCHEMBL910914 0.80 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108495815-A The synthesis of molecular sieve SSZ-98 雪佛龙美国公司 2018-09-04 — — CN claimed
US-10914987-B2 Complex and optical element KYOTO UNIVERSITY (JP) 2021-02-09 — — US disclosed
US-20200241336-A1 COMPLEX AND OPTICAL ELEMENT KYOTO UNIVERSITY (JP) 2020-07-30 — — US disclosed
US-20190270756-A1 6-MEMBERED URACIL ISOSTERES CV6 THERAPEUTICS (NI) LIMITED (GB) 2019-09-05 — — US disclosed
US-10172858-B2 Combination pharmaceutical compositions and uses thereof INTELLIKINE LLC (US) 2019-01-08 — — US disclosed
CN-108495815-A The synthesis of molecular sieve SSZ-98 雪佛龙美国公司 2018-09-04 — — CN disclosed
US-8399485-B2 Acyl bipiperidinyl compounds useful as GPR 119 agonists MERCK SHARP & DOHME CORP. (US) 2013-03-19 — — US disclosed
US-20130034521-A1 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2013-02-07 — — US disclosed
US-20120263678-A1 1'-SUBSTITUTED PYRIMIDINE N-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-10-18 — — US disclosed
US-8106066-B2 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof MEMORY PHARMACEUTICALS CORPORATION (US) 2012-01-31 — — US disclosed
US-7842672-B2 Phosphonate inhibitors of HCV GILEAD SCIENCES, INC. (US) 2010-11-30 — — US disclosed
US-20100022467-A1 ANTI-CANCER PHOSPHONATE ANALOGS BOOJAMRA CONSTANTINE G 2010-01-28 — — US disclosed
US-20090306112-A1 ANTIVIRAL PROTEASE INHIBITORS GILEAD SCIENCES, INC. (US) 2009-12-10 — — US disclosed
US-20090247488-A1 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS CANNIZZARO CARINA 2009-10-01 — — US disclosed
US-20090156558-A1 PHOSPHONATE ANALOGS OF ANTIMETABOLITES FARDIS MARIA 2009-06-18 — — US disclosed
US-20080107628-A1 Polymerase inhibitors GILEAD SCIENCES, INC. 2008-05-08 — — US disclosed
US-7300924-B2 Anti-infective phosphonate analogs GILEAD SCIENCES, INC. (US) 2007-11-27 — — US disclosed
US-20070072809-A1 Antiviral compounds GILEAD SCIENCES, INC. 2007-03-29 — — US disclosed
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds GILEAD SCIENCES, INC. 2007-01-11 — — US disclosed
EP-0056144-A1 Carboxylic acid derivatives, their preparation and use as pharmaceuticals Dr. Karl Thomae GmbH (DE) 1982-07-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156558-A1 PHOSPHONATE ANALOGS OF ANTIMETABOLITES TYMP, PHOSPHO1, PHPT1 CPN1 1513/4885CPB2 1424/4885SHBG 486/4885
US-20070072809-A1 Antiviral compounds MAVS, EIF2AK2, ZC3HAV1 CPN1 593/4885CPB2 1852/4885SHBG 4295/4885
US-20120263678-A1 1'-SUBSTITUTED PYRIMIDINE N-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT PNP, NUDT1, TYMP CPN1 216/4885CPB2 1562/4885SHBG 4827/4885
US-20080107628-A1 Polymerase inhibitors POLR2H, POLR2E, POLR1E CPN1 548/4885CPB2 311/4885SHBG 3788/4885
US-20130034521-A1 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT PNP, MTAP, SLC29A1 CPN1 209/4885CPB2 2103/4885SHBG 4683/4885
US-20090247488-A1 ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS PHOSPHO1, TNF, PTGES CPN1 1660/4885CPB2 623/4885SHBG 1754/4885
US-20190270756-A1 6-MEMBERED URACIL ISOSTERES UNG, DUT, DPYD CPN1 1415/4885CPB2 3093/4885SHBG 4436/4885
US-20100022467-A1 ANTI-CANCER PHOSPHONATE ANALOGS PIK3CA, PHOSPHO1, PTEN CPN1 2262/4885CPB2 3543/4885SHBG 3373/4885
US-20090306112-A1 ANTIVIRAL PROTEASE INHIBITORS ACE, DNPEP, TMPRSS15 CPN1 30/4885CPB2 87/4885SHBG 4003/4885
US-10172858-B2 Combination pharmaceutical compositions and uses thereof CDC25C, CCNC, CDC25B CPN1 3238/4885CPB2 2832/4885SHBG 2026/4885
US-20070010489-A1 Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds PPA1, PNP, PPME1 CPN1 144/4885CPB2 445/4885SHBG 4296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.