Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480070 | 0.83 | SLC6A4 (0.43) | MEN1KMT2ASLC6A4HTR1AHTR2A | |
| SCHEMBL473994 | 0.82 | SLC6A4 (0.45) | MEN1KMT2ASLC6A4HTR1AHTR2A | |
| SCHEMBL14793744 | 0.81 | L3MBTL1 (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3312341 | 0.81 | KMT2A (0.45) | MEN1KMT2AAPLNRPOLBIDO1 | |
| SCHEMBL584252 | 0.81 | APLNR (0.59) | MEN1KMT2AHTR2AAPLNRIDO1 | |
| SCHEMBL910548 | 0.80 | POLB (0.62) | POLBALDH1A1ERN1TRIM24TYR | |
| SCHEMBL9921242 | 0.79 | SLC6A4 (0.45) | MEN1KMT2ASLC6A4HTR1AHTR2A | |
| SCHEMBL16670512 | 0.78 | BACE1 (0.45) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8340513 | 0.78 | SLC6A4 (0.47) | SLC6A4HTR1AHTR2AKCNH2APLNR | |
| SCHEMBL22078669 | 0.78 | CA12 (0.41) | MEN1KMT2ASLC6A4HTR1AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102548976-B | (thio) morpholine derivatives as S1P modulators | ABBVIE BAHAMAS LTD. (BS) | 2015-09-09 | — | — | CN | disclosed |