Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13678722 | 0.84 | APLNR (0.39) | KMT2AMEN1ALDH1A1HPGDAPOBEC3A | |
| SCHEMBL584252 | 0.83 | APLNR (0.59) | KMT2AMEN1ALDH1A1APLNRADRA1A | |
| SCHEMBL2559819 | 0.82 | HTT (0.45) | KMT2AMEN1ALDH1A1HTTHPGD | |
| SCHEMBL910548 | 0.81 | POLB (0.62) | ALDH1A1HPGDPOLBERN1TRIM24 | |
| SCHEMBL28034772 | 0.81 | MEN1 (0.42) | KMT2AMEN1ALDH1A1APLNRPOLB | |
| SCHEMBL26551206 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1HTTHPGD | |
| SCHEMBL7332987 | 0.79 | ADRA1A (0.62) | ALDH1A1ADRA1ATAAR1IDO1 | |
| SCHEMBL13678723 | 0.79 | POLB (0.35) | KMT2AMEN1POLBTRIM24TYR | |
| SCHEMBL31664401 | 0.79 | SMN1; SMN2 (0.39) | ALDH1A1 | |
| SCHEMBL585890 | 0.78 | KDM4E (0.40) | KMT2AMEN1ALDH1A1HTTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113616-A1 | INHIBITION OF DISCOLORATION BY WASHING AND CLEANING AGENTS AND/OR COSMETIC AGENTS | HENKEL AG & CO. KGAA (DE) | 2010-05-06 | — | — | US | disclosed |
| US-20080226708-A1 | Silicone Vesicles Containing Actives | DOW CORNING CORPORATION | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080226708-A1 | Silicone Vesicles Containing Actives | EXOSC5, EXOSC9, EXOSC10 | KMT2A 2234/4885MEN1 574/4885ALDH1A1 4797/4885 |
| US-20100113616-A1 | INHIBITION OF DISCOLORATION BY WASHING AND CLEANING AGENTS AND/OR COSMETIC AGENTS | CACNA1I, CACNA1G, CACNA1F | KMT2A 1472/4885MEN1 753/4885ALDH1A1 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.