Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12156965 | 0.91 | TDP1 (0.42) | TDP1TP53ALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL29094042 | 0.82 | ACHE (0.31) | — | |
| SCHEMBL11021176 | 0.80 | RAB9A (0.31) | ALDH1A1CYP1A2CYP2A6SMN1; SMN2 | |
| SCHEMBL6587771 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL11110746 | 0.80 | RAB9A (0.31) | ALDH1A1CYP1A2CYP2A6SMN1; SMN2 | |
| SCHEMBL9947629 | 0.80 | CYP3A4 (0.36) | TP53CYP2A6RAPGEF4SMN1; SMN2 | |
| SCHEMBL10667614 | 0.79 | PDE2A (0.39) | ALDH1A1RAPGEF4 | |
| SCHEMBL11522076 | 0.78 | ACHE (0.42) | TDP1ALDH1A1CYP2A6SMN1; SMN2 | |
| SCHEMBL10594860 | 0.78 | NFE2L2 (0.33) | ALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL3136387 | 0.77 | HTT (0.37) | ALDH1A1CYP1A2CYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116924870-A | Synthesis method of 1-substituted phenanthrene compound | 西北师范大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-105120865-A | Muscarinic agonists | ACADIA PHARM INC | 2015-12-02 | — | — | CN | disclosed |