Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | MPO | P05164 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750005 | 0.80 | HTR1A (0.63) | HTR1DHTR2AMPOHTR1AHTR1B | |
| Hydrochloric Acid SCHEMBL2990516 | 0.79 | HTR1A (0.62) | HTR1DHTR2AMPOHTR1AHTR1B | |
| SCHEMBL27548485 | 0.77 | MAOB (0.47) | HTR1DHTR2AMPOHTR2CCYP2D6 | |
| SCHEMBL17927600 | 0.77 | CYP2D6 (0.55) | HTR1DHTR2AMPOHTR1AHTR1B | |
| SCHEMBL2648422 | 0.77 | ALDH1A1 (0.66) | HTR2AHTR1AHTR1BHTR2CKDM4E | |
| SCHEMBL12606899 | 0.76 | MTNR1A (0.70) | MPOHTR1ACYP2D6KDM4EMEN1 | |
| SCHEMBL28035248 | 0.74 | SLC6A4 (0.64) | HTR1ASLC6A4 | |
| SCHEMBL9372571 | 0.72 | HTR2A (0.45) | HTR1DHTR2AMPOHTR1AHTR1B | |
| SCHEMBL5784762 | 0.72 | KIF11 (0.47) | KDM4EMEN1KMT2ACYP1A2MAPT | |
| SCHEMBL29954011 | 0.71 | ALDH1A1 (0.62) | KDM4EKMT2ACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1729174-B | The synthesis of amine and the intermediate for the synthesis of amine | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2015-10-21 | — | — | CN | disclosed |