SCHEMBL28035602

SCHEMBL28035602

CC(C)(OC=O)c1ccccc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
PTGS2 P35354 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34
FFAR4 Q5NUL3 1/20 0.33
ALDH1A1 P00352 5/20 0.33
MITF O75030 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 2/20 0.32
MAPK1 P28482 2/20 0.32
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4487866 0.82 ADRB2 (0.33) PTGS2FFAR4ALDH1A1HSD17B10MAPK1
Tert-Butyl Formate SCHEMBL27794875 0.79 TDP1 (0.46) TDP1PPARGPPARAALDH1A1MAPT
Biphenyl SCHEMBL27794837 0.78 TDP1 (0.62) TDP1PTGS2CYP2C9CYP2C19ALDH1A1
SCHEMBL28035672 0.78 S1PR1 (0.33) TDP1ALDH1A1MAPTMEN1KMT2A
SCHEMBL28035600 0.78 CSNK2A1 (0.34) TDP1MEN1KMT2A
SCHEMBL29278360 0.77 ALDH1A1 (0.44) TDP1PTGS2CYP2C9ALDH1A1MAPT
SCHEMBL5068618 0.77 ALDH1A1 (0.37) PTGS2ALDH1A1MITFMAPTHTT
Tert-Butyl Formate SCHEMBL28032597 0.77 TDP1 (0.59) TDP1CYP2C9CYP2C19ALDH1A1MAPT
SCHEMBL18297950 0.76 HSD11B1 (0.37) PTGS2CYP2C9CYP2C19PPARGPPARD
Acetaldehyde SCHEMBL27656697 0.76 TRPA1 (0.41) TDP1PTGS2ALDH1A1NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105330541-B The synthetic method of the alkyl formate of 4 ' halogenated methyl biphenyl 2 常州博世伟业生物科技有限公司 2017-09-12 CN disclosed
CN-105330541-A Synthesis method of 4'-halogenated methylbiphenyl-2-formic aid alkyl ester CHANGZHOU BOSHI WEIYE BIOTECHNOLOGY CO LTD 2016-02-17 CN disclosed