Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 11/20 | 0.58 |
| ▸ | ACVR1 | Q04771 | 11/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.53 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.53 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.53 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154835 | 0.76 | ADRB1 (0.57) | TGFBR1ACVR1 | |
| Hydrochloric Acid SCHEMBL28035691 | 0.74 | ALK (0.64) | TGFBR1ACVR1FYNALKRIPK2 | |
| SCHEMBL1992377 | 0.74 | CHRNB2 (0.64) | — | |
| SCHEMBL12714792 | 0.74 | CHRNB2 (0.58) | TGFBR1ACVR1 | |
| SCHEMBL10075919 | 0.74 | HTR7 (0.71) | ALK | |
| SCHEMBL17110789 | 0.74 | ACVR1 (1.00) | TGFBR1ACVR1FYNRIPK2BMPR1A | |
| SCHEMBL2387128 | 0.74 | MET (0.55) | TGFBR1ACVR1FYNALK | |
| SCHEMBL18613408 | 0.73 | FYN (1.00) | TGFBR1ACVR1FYNRIPK2NOD2 | |
| SCHEMBL361649 | 0.73 | ADRB1 (0.61) | TGFBR1ACVR1 | |
| Hydrochloric Acid SCHEMBL21045786 | 0.73 | CHRNB2 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968654-A | Substituted 2-aminopyridine protein kinase inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2015-10-07 | — | — | CN | disclosed |