Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726068 | 0.85 | TAS2R14 (0.54) | TAS2R14CTSSDHODHHDAC6LMNA | |
| SCHEMBL28327188 | 0.83 | TAS2R14 (0.49) | TAS2R14CTSSDHODHHDAC6LMNA | |
| SCHEMBL27976262 | 0.83 | TAS2R14 (0.49) | TAS2R14CTSSDHODHHDAC6LMNA | |
| SCHEMBL28052031 | 0.80 | TAS2R14 (0.55) | TAS2R14CTSSDHODHHDAC6LMNA | |
| SCHEMBL697951 | 0.79 | TAS2R14 (0.67) | TAS2R14CTSSDHODHHDAC6LMNA | |
| SCHEMBL29656425 | 0.79 | TAS2R14 (0.54) | TAS2R14CTSSDHODHHDAC6LMNA | |
| SCHEMBL12327907 | 0.79 | TAS2R14 (0.54) | TAS2R14CTSSDHODHHDAC6LMNA | |
| SCHEMBL20267165 | 0.78 | ALDH1A1 (0.58) | TAS2R14CTSSLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL15352107 | 0.77 | TAS2R14 (0.65) | TAS2R14CTSSDHODHHDAC6LMNA | |
| SCHEMBL5370256 | 0.77 | TAS2R14 (0.53) | TAS2R14CTSSDHODHHDAC6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143193-A | Biaryl or heterocyclic biaryl substituted cyclohexene derivative compounds as CETP inhibitors | CHONG KUN DANG PHARM CORP | 2015-12-09 | — | — | CN | disclosed |