Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27974641 | 0.78 | CES2 (0.53) | RAB9ANPC1CES2CES1ALDH1A1 | |
| SCHEMBL28682238 | 0.77 | PGR (0.53) | RAB9AATMNPC1MAPTMAPK1 | |
| Metamfepramone SCHEMBL10505245 | 0.77 | PGR (0.63) | RAB9AATMNPC1MAPTMAPK1 | |
| Metamfepramone SCHEMBL309430 | 0.77 | PGR (0.63) | RAB9AATMNPC1MAPTMAPK1 | |
| SCHEMBL10716596 | 0.76 | ATM (0.55) | RAB9AATMNPC1MAPTLMNA | |
| SCHEMBL2329814 | 0.76 | ATM (0.55) | RAB9AATMNPC1MAPTLMNA | |
| Metamfepramone SCHEMBL5172661 | 0.75 | PGR (0.61) | RAB9AATMNPC1MAPTMAPK1 | |
| SCHEMBL29273682 | 0.75 | RAB9A (0.49) | RAB9AATMNPC1MAPTMAPK1 | |
| Metamfepramone SCHEMBL22614741 | 0.75 | PGR (0.61) | RAB9AATMNPC1MAPTMAPK1 | |
| SCHEMBL11107521 | 0.75 | MAPT (0.49) | RAB9AATMNPC1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968654-A | Substituted 2-aminopyridine protein kinase inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2015-10-07 | — | — | CN | disclosed |