Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | GRM6 | O15303 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975859 | 0.91 | ALDH1A1 (0.37) | GRM6KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL28036416 | 0.87 | PTGS2 (0.47) | KDM4EMAPTLMNAMAPK1NPSR1 | |
| SCHEMBL27975579 | 0.85 | TP53 (0.43) | MAPTMAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL27975546 | 0.85 | ALDH1A1 (0.40) | GRM6KDM4EMAPTLMNAMAPK1 | |
| SCHEMBL27975865 | 0.83 | TAAR1 (0.46) | GRM6KDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL28036417 | 0.82 | ACHE (0.46) | MAPTLMNAMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL28036395 | 0.81 | ALDH1A1 (0.35) | GRM6KDM4EMAPTLMNAMAPK1 | |
| SCHEMBL27975857 | 0.81 | MAPT (0.52) | MAPTLMNAMAPK1NPSR1SMN1; SMN2 | |
| SCHEMBL28036701 | 0.80 | SIRT1 (0.40) | KDM4EMAPTLMNANPSR1ALDH1A1 | |
| SCHEMBL27975539 | 0.77 | ALDH1A1 (0.37) | KDM4EMAPTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980248-B | 3,5-bis-substituted-4-amino thiophene-2-formaldehyde compound and preparation method thereof | ZHEJIANG UNIVERSITY (CN) | 2015-11-18 | — | — | CN | disclosed |